Radiation ― A Double-Edged Sword

Radiation is a well-known carcinogen to humans, yet it remains valuable for diagnosis and treatment. To uncover the molecular mechanisms behind this double-edged effect on human health, we are conducting cutting-edge research using a variety of approaches, including microbeams, animal models, and large-scale cohorts. Our overarching aim is to both develop next-generation radiotherapeutic technologies and establish personalized systems for assessing radiation risk.

Hisanori Fukunaga, MD, PhD

Principal Investigator

News

August 13, 2025

Our research paper has been published online in International Journal of Molecular Sciences.

Seino R, Fukunaga H. Deep Learning-Based Imaging Analysis Reveals Radiation-Induced Bystander Effects on Cancer Cell Migration and the Modulation by Cisplatin .

Click here for the journal website of our article.

July 18, 2025

Our research paper has been published online in Journal of Cell Science.

Seino R, Nishikubo K, Fukunaga H. Cell cycle- and dose-dependent effects on mitochondrial DNA copy number variation following irradiation .

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May 23, 2025

Congratulations to Mr. Noritsugu Abe, a former research student, on receiving the 29th RADIOISOTOPES Research Promotion Award for Young Scientists from the Japan Radioisotope Association!

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May 11, 2025

Our research paper has been published online in Journal of Radiation Research.

Kaminaga K, Fukunaga H, Hirose E, Watanabe R, Suzuki K, Prise KM, Yokoya A. Time-lapse imaging of cells in spatially fractionated X-ray fields using a mini beam as an alternative to accelerator-based sub-millimeter beams .

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April 23, 2025

Our research paper has been published online in Japanese Journal of Clinical Oncology.

Fukunaga H, Fukunaga M. Mitochondrial DNA copy numbers in gastric cancer tissues: a possible biomarker for estimating cancer progression.

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April 1, 2025

Welcome to newcomers (3 undergraduate students, 1 research student, and 1 graduate student), who have joined the Fukunaga lab.