Radiation ― A Double-Edged Sword

Radiation is a well-known carcinogen to humans, yet it remains valuable for diagnosis and treatment. To uncover the molecular mechanisms behind this double-edged effect on human health, we are conducting cutting-edge research using a variety of approaches, including microbeams, animal models, and large-scale cohorts. Our overarching aim is to both develop next-generation radiotherapeutic technologies and establish personalized systems for assessing radiation risk.

Hisanori Fukunaga, MD, PhD

Principal Investigator

News

May 23, 2025

Congratulations to Mr. Noritsugu Abe, a former research student, on receiving the 29th RADIOISOTOPES Research Promotion Award for Young Scientists from the Japan Radioisotope Association!

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May 11, 2025

Our research paper has been published online in Journal of Radiation Research.

Kaminaga K, Fukunaga H, Hirose E, Watanabe R, Suzuki K, Prise KM, Yokoya A. Time-lapse imaging of cells in spatially fractionated X-ray fields using a mini beam as an alternative to accelerator-based sub-millimeter beams .

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April 23, 2025

Our research paper has been published online in Japanese Journal of Clinical Oncology.

Fukunaga H, Fukunaga M. Mitochondrial DNA copy numbers in gastric cancer tissues: a possible biomarker for estimating cancer progression.

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April 1, 2025

Welcome to newcomers (3 undergraduate students, 1 research student, and 1 graduate student), who have joined the Fukunaga lab.

March 2024

Our research paper has been published online in Japanese Journal of Health Physics.

Abe N, Seino R, Ikeda A, Fukunaga H. Radiation knowledge and anxiety: An online survey of construction workers and radiological technologists (Japanese).

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February 26, 2025

Congratulations to Mr. Noritsugu Abe, a research student, on receiving the Best Research Award at the 80th Autumn Meeting of the Hokkaido Branch, Japanese Society of Radiological Technology!

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February 15, 2025

Our research paper has been published online in RADIOISOTOPES.

Abe N, Seino R, Fukunaga H. X-ray exposed tubulins during in vitro polymerization reactions: A possible approach for radiation-induced impacts on microtubules (Japanese).

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February 2, 2025

Our research paper has been published online in Environment International.

Seino R, Kubo H, Nishikubo K, Fukunaga H. Radiation-induced impacts on mitochondrial DNA and the transgenerational genomic instability.

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Click here for the press release (Japanese).

January 31, 2025

Our research paper has been published online in Biomedical Research.

Muramatsu H, Seino R, Fukunaga H. Mitochondrial DNA copy number variation in Epstein-Barr virus transformed B cells after exposure to radiation: A possible biomarker for dosimetry.

Click here for the journal website of our article.